Hypolipidemic effects of orally administered dextran and cellulose anion exchangers in cockerels and dogs.

P1: Dextran Curcumin Promotes Novel Object Recognition Memory in Rats after Ischemic Stroke

Ischemic stroke causes the depletion of energy and induces excitotoxicity and neuroinflammation in the brain that results from thrombotic blockage. Cerebral ischemia leads to many types of memory loss, including impairment of working, spatial and object recognition memoreis. Curcumin shows strong anti-oxidoinflammatory activities but it terapathics limited by its low solubility in water and cor...

The metabolism of orally administered 4-methyl-2-thiouracil in cockerels.

A preliminary study on some potential toxic effects of Rosa damascena Mill

Rosa damascena has been traditionally used as an herbal medicine for different therapeutic purposes. Inorder to preliminarily study the probable toxic effects of the plant, its infusion was orally administered to 5groups of 5 dogs at doses 0.5-8 times that of human use in traditional medicine (90-1440 mg/kg/d) for 10successive days. The dogs in the control group (n=4) received placebo. Serum le...

Effects of Black Plum (Vitex doniana) Leaf Meal Inclusion on Performance, Haematology and Serum Biochemical Indices of Cockerels

A total of 105, 14 weeks old cockerels weighing 1.49 ± 0.023 kg were used to investigate the effects of Vitex doniana leaf meal (VDLM) on performance, haematological and serum biochemical parameters in cockerels over a seven-week experimental trials. The cockerels were divided into three (3) treatment groups of 0%, 5% and 10% inclusion levels of VDLM in a completely randomized design layout. Th...

Mucosal Adjuvant Potential of Quillaja saponins and Cross-linked Dextran Microspheres, Co-administered with Liposomes Encapsulated with Tetanus Toxoid

Intranasal vaccination is particularly a striking route for mucosal immunization, due to the ease of administration and the induction of both mucosal and humoral immunity. However, soluble antigens (Ag) are not sufficiently taken up after the nasal administration and need to be co-administered with adjuvants, penetration enhancers or encapsulated in particles. So, in this study, tetanus toxoid ...